Cla Affect on Body Fat Mass

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How Does the Supplementation of Conjugated Linoleic Acid (CLA) affect Human Fat Mass?

Abstract
Research Question: How does the supplementation of conjugated linoleic acid (CLA) affect human body composition? Literature Review: Conjugated linoleic acid (CLA) refers to a family of geometrical and positional isomers of linoleic acid. The predominant sources of CLA are from ruminant animal fats (cow, dairy, sheep, goat, and deer). Over the past 20 years, CLA supplementation has produced positive effects in animal studies, such as significant body fat reduction, anticarcinogenisis, antiatherogenesis, immune modulation and improved bone health. Conversely, human studies have not produced all of the aforementioned results. Nonetheless, there have been many human studies supporting a minimal but significant body fat reduction. These results have been mainly attained with a 50:50 mixture of cis-9, trans-11 and trans-10, cis-12 of purified CLA isomers at various doses. There is evidence indicating that a dose of 3.0g CLA/day may lead to fat loss, whereas the average Canadian consumes between 0.1-1.5 g CLA/day. Therefore, a supplement may be warranted in the future, once further research has been completed on the efficacy and safety of CLA supplementation. Implications to dietetic practice: Clinical dietitians involved in research should experiment with various doses and isomers, but they should particularly investigate the long-term implications of such supplementation. Community dietitians should teach community members how to select natural health products, avoiding inconclusive products like CLA. Administrative dietitians should continue to plan menus based on Canada’s Food Guide, while ignoring CLA claims. Recommendation: In terms of policy, natural health product regulations should be revised, where products sold in Canada…...

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